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PFAS Sample Preparation: Extraction & Concentration

TurboTrace- EPA 1633 PFAS Extraction, Wastewater Analysis
One-Step PFAS Sample Prep for Food. All sample Prep in under 2 hours
EconTrace - PFAS Extraction for Water Analysis
EzPFC - Semi-Automated PFAS Extraction
PFAS Concentrator /Evaporator
PFAS Certified Cartridges

 

PFAS Sample Preparation: Extraction, Clean-up & Concentration

          Certified PFAS Cartridges▼     PFAS Total Prep – food▼       PFAS Concentrators▼     Semi-Automated EZPFC ▼     Automated EconoTrace – Water ▼     Automated TurboTrace EPA 1633 ▼ 
 

PFAS Extraction: Origins and Concerns

Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals used in firefighting foams, non-stick cookware, water-repellent fabrics, and food packaging. Their resistance to heat, water, and oil makes them valuable in many industries, but also contributes to their persistence in the environment and human body, earning them the name “forever chemicals.” Exposure to certain PFAS has been linked to liver damage, thyroid disease, and an increased risk of cancer, making their detection and regulation a public health priority. As PFAS contamination spreads through water, soil, food, and biological systems, accurate analytical methods are essential for effective monitoring and mitigation efforts.

PFAS Sample Preparation Challenges

The analysis of PFAS is complex due to their chemical stability, extremely low detection limits, and high risk of contamination from laboratory equipment and environmental sources. Effective sample preparation is crucial to ensuring accuracy and preventing cross-contamination. Solid Phase Extraction (SPE) is widely used to isolate PFAS from water, soil, food, and biological samples, providing clean extracts for analysis. Standardized methods such as EPA 537.1, EPA 533, EPA 1633 and ISO 21675 offer protocols to ensure reliable, reproducible results in laboratories worldwide, helping scientists accurately assess PFAS contamination in various matrices.

See More . . .

Automated PFAS Extraction - Methos 1633
Wastewater Analysis

The TurboTrace® PFC SPE System is a fully automated sample preparation solution designed for the solid-phase extraction (SPE) of per- and polyfluoroalkyl substances (PFAS) from wastewater and other complex matrices. This system processes up to eight samples simultaneously, ensuring consistent and reproducible results while minimizing the need for sample reruns.

See More . . .

EzPFC /6 Samples

The EZPFC PFAS Extraction System is a revolutionary solution designed for laboratories focused on Per- and Polyfluoroalkyl Substances (PFAS) analysis. This compact, cost-effective, and user-friendly system automates and streamlines the Solid Phase Extraction (SPE) process for PFAS analysis, ensuring consistent and accurate results every time.

Using vacuum & nitrogen, the EZPFC automatically loads the samples, rinses the sample bottle and delivers the solvent to the SPE cartridges. The final extract is delivereddirectly to the extract vial ready for final concentration in the FMS SuperVap®. The process saves both labor and time.

The ultimate rewards are saving labor and time

See More . . .

Comprehensive PFAS Sample Prep Solutions

FMS provides a complete suite of automated EPA Method 1633 solutions, ranging from starter kits with certified consumables to semi-automated and fully automated extraction and concentration systems. Our cutting-edge technology reduces contamination risks, enhances efficiency, and ensures reproducible recoveries—making PFAS analysis more precise and reliable.

Whether your lab requires a cost-effective manual setup or a high-throughput automated workflow, FMS delivers scalable solutions designed to improve accuracy, efficiency, and consistency in environmental, food, and biological testing applications.

Our certified systems include:

TurboTrace® (wastewater), EconoTrace® (drinking water), EzPFC™ (semi-automated),  FMS PFAS Starter Kit and the SuperVap


In-House LC-MS & GC-MS Testing: Guaranteeing Purity and Performance

To ensure the highest purity in our products and consumables, FMS conducts in-house testing using advanced LC-MS and GC-MS instrumentation. Our laboratory rigorously tests raw materials, monitors in-process manufacturing, and verifies final products to eliminate contamination.

By integrating real-time quality control, we uphold strict purity standards—providing laboratories with reliable, interference-free results.

Additionally, FMS offers a one-step PFAS sample preparation solution including extraction, purification, and concentration, delivering PFAS-ready extracts from sample to vial. This automated workflow streamlines testing, allowing laboratories to move directly to analysis with minimal handling and maximum accuracy.

One-Step PFAS Total-Prep
Extraction + CleanUp + Concentration
For Food Analysis

One-Step PFAS Total-Prep is an integrated sample-preparation solution designed to extract, clean up, and concentrate PFAS from challenging food matrices such as meat and fish in a single, streamlined workflow. By replacing multiple manual steps with a unified, controlled process, it reduces hands-on time, improves reproducibility, and minimizes contamination risk. The system combines optimized extraction and SPE cleanup with PFAS-safe components and certified consumables to deliver clean, LC/MS-ready extracts in hours rather than days. Built for reliability and low background performance, One-Step PFAS Total-Prep ensures consistent, high-quality results for routine and advanced PFAS food analysis.

Read More . . .

Automated PFAS Extraction for Water Analysis

The EconoTrace® PFC is an automated Parallel Solid Phase Extraction (SPE) system designed for the efficient extraction of per- and polyfluoroalkyl substances (PFAS) from drinking water. It streamlines laboratory workflows by automating sample preparation, thereby enhancing productivity and ensuring consistent, high-quality results.

See More . . .

SuperVap PFAS Concentrator/Evaporator

The SuperVap/PFC is a fully automated, direct-to-vial concentrator designed for PFAS analysis and other demanding applications. By replacing traditional manual evaporation methods, it enhances efficiency, consistency, and sample integrity while reducing labor costs. The system features a waterless dry bath, programmable controls, high-throughput capacity (up to 24 samples), and integrated HEPA/carbon filtration to minimize contamination. All components are rigorously tested to ensure a contaminant-free and clean blank for PFAS analysis, delivering reproducible, high-quality results.

Read More . . .

PFAS Extraction: Origins and Concerns

Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals used in firefighting foams, non-stick cookware, water-repellent fabrics, and food packaging. Their resistance to heat, water, and oil makes them valuable in many industries, but also contributes to their persistence in the environment and human body, earning them the name “forever chemicals.” Exposure to certain PFAS has been linked to liver damage, thyroid disease, and an increased risk of cancer, making their detection and regulation a public health priority. As PFAS contamination spreads through water, soil, food, and biological systems, accurate analytical methods are essential for effective monitoring and mitigation efforts.

PFAS Sample Preparation Challenges

The analysis of PFAS is complex due to their chemical stability, extremely low detection limits, and high risk of contamination from laboratory equipment and environmental sources. Effective sample preparation is crucial to ensuring accuracy and preventing cross-contamination. Solid Phase Extraction (SPE) is widely used to isolate PFAS from water, soil, food, and biological samples, providing clean extracts for analysis. Standardized methods such as EPA 537.1, EPA 533, EPA 1633 and ISO 21675 offer protocols to ensure reliable, reproducible results in laboratories worldwide, helping scientists accurately assess PFAS contamination in various matrices.

 

Comprehensive PFAS Sample Prep Solutions

FMS provides a complete suite of PFAS sample preparation solutions, ranging from starter kits with certified consumables to semi-automated and fully automated extraction and concentration systems. Our cutting-edge technology reduces contamination risks, enhances efficiency, and ensures reproducible recoveries, making PFAS analysis more precise and reliable. Whether your lab requires a cost-effective manual setup or a high-throughput automated workflow, FMS delivers scalable solutions designed to improve accuracy, efficiency, and consistency in environmental, food, and biological testing applications.

In-House LC-MS & GC-MS Testing: Guaranteeing Purity and Performance

To ensure the highest purity in our products and consumables, FMS conducts in-house testing using advanced LC-MS and GC-MS technology. Our laboratory rigorously tests raw materials, monitors in-process manufacturing, and verifies final products to eliminate contamination. By integrating real-time quality control, we uphold strict purity standards, providing laboratories with reliable, interference-free results. Additionally, FMS offers a one-step PFAS sample preparation solution, including extraction, purification, and concentration, delivering PFAS-ready extracts from sample to vial. This automated workflow streamlines testing, allowing laboratories to move directly to analysis with minimal handling and maximum accuracy.

Automated PFAS Sample Prep for Food Analysis

A fully automated PFAS extraction, cleanup, and concentration system for meat, fish, and food samples—delivering high-quality results in under 3 hours with minimal hands-on time.
Designed specifically for complex food matrices, this streamlined workflow eliminates multiple manual steps, reduces contamination risk, and provides consistent, reproducible recoveries for all major PFAS analytes. Laboratories can process samples faster, maintain tighter quality control, and achieve lower reporting limits with ease.

See More . . .

Automated PFAS Extraction for Wastewater Analysis

The TurboTrace® PFC SPE System is a fully automated sample preparation solution designed for the solid-phase extraction (SPE) of per- and polyfluoroalkyl substances (PFAS) from wastewater and other complex matrices. This system processes up to eight samples simultaneously, ensuring consistent and reproducible results while minimizing the need for sample reruns.

See More . . .

Automated PFAS Extraction for water Analysis

The EconoTrace® PFC is an automated Parallel Solid Phase Extraction (SPE) system designed for the efficient extraction of per- and polyfluoroalkyl substances (PFAS) from drinking water. It streamlines laboratory workflows by automating sample preparation, thereby enhancing productivity and ensuring consistent, high-quality results.

See More . . .

EzPFC Semi-Auomatic Extraction

The EZPFC PFAS Extraction System is a revolutionary solution designed for laboratories focused on Per- and Polyfluoroalkyl Substances (PFAS) analysis. This compact, cost-effective, and user-friendly system automates and streamlines the Solid Phase Extraction (SPE) process for PFAS analysis, ensuring consistent and accurate results every time.

Using vacuum & nitrogen, the EZPFC automatically loads the samples, rinses the sample bottle and delivers the solvent to the SPE cartridges. The final extract is delivereddirectly to the extract vial ready for final concentration in the FMS SuperVap®. The process saves both labor and time.

The ultimate rewards are saving labor and time

See More . . .

SuperVap PFAS Concentrator/Evaporator

The SuperVap/PFC is a fully automated, direct-to-vial concentrator designed for PFAS analysis and other demanding applications. By replacing traditional manual evaporation methods, it enhances efficiency, consistency, and sample integrity while reducing labor costs. The system features a waterless dry bath, programmable controls, high-throughput capacity (up to 24 samples), and integrated HEPA/carbon filtration to minimize contamination. All components are rigorously tested to ensure a contaminant-free and clean blank for PFAS analysis, delivering reproducible, high-quality results.

Read More . . .

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About FMS

Fluid Management Systems (FMS) specializes in designing, manufacturing, and marketing state-of-the-art sample preparation systems that are simple, quick, and cost-effective. Our comprehensive solutions encompass extraction, cleanup, and concentration processes, delivering total sample preparation from sample to vial. With a range of high-speed, high-throughput systems, we cater to various budgets and needs, ensuring efficient and reliable sample analysis. ​fms-inc.com

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FLUID MANAGEMENT SYSTEMS, INC. 900 Technology Park Drive BILLERICA, MA 01821 T: +1 (617) 393-2396 F: +1 (617) 393-0194 BY E-MAIL: FOR ALL SALES INQUIRIES: SALES@FMS-INC.COM