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  • Home
  • Automated Dioxin Cleanup
    • Automated EzPrep+ Dioxin Cleanup
    • EconoPrep Dioxin Sample Clean-Up
    • Dioxin Sample Clean-up
    • SemiAutomated EzPrep Dioxin Cleanup
  • PFAS Extraction
    • PFAS Extraction
    • Automated PFAS Extraction
    • PFAS Extraction for Wastewaters Analysis
    • PFAS Extract Starter Kit
    • PFAS Concentrator /Evaporator
  • Pressurized Liquid Extraction
    • PLE- Pressurized Liquid Extraction
    • Plant Extraction
  • Automated SPE
    • Automated SPE Solutions
    • Drugs of Abuse Sample Prep
    • OIL and Grease Extraction
    • Solid Phase Extraction for Water Analysis
    • Semi-Automated Solid Phase Extraction
  • Concentrator/ Evaporator
    • SuperVap 6- position
    • SuperVap 12 Position
    • SuperVap – 24 position
    • SuperVap PFC-24
  • EzPrep Products
  • Automated Sample Preparation
  • Explore
    • Applications
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    • Contact Us

Automated

Solid Phase Extraction System

Versatile, Programmable SPE for Pharmaceutical, Diagnostic & Biotech

Automated SPE Solutions

Drugs of abuse Sample Prep

Oil & Grease  Extraction

Automated SPE – Water Analysis

Semi-Automated SPE 

EzSPE Applications   

AutoSPE

Automated Solid Phase Extraction

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Brochure   |   Application Notes   

Automated Solid Phase Extraction System

Versatile, Programmable SPE for Pharmaceutical, Diagnostic & Biotech Workflows

Automated SPE  Solutions      Drugs of  Abuse Sample Prep      Oil & Grease  Extraction        Automated SPE – Water Analysis      Semi-Automated SPE       EzSPE Applications

SPE automation Solution rev-10

Brochure   Applications

Automated Solid Phase Extraction–AutoSPE

Automated Solid Phase Extraction – AutoSPE delivers a modular, programmable solution for laboratories requiring precise, reproducible, and efficient sample preparation. Designed for pharmaceutical, environmental, food safety, biotech, clinical, and diagnostic workflows, AutoSPE simplifies complex SPE protocols and reduces hands-on time—making it ideal for both method development and high-throughput production environments.

AutoSPE – Simplified Sample Prep

The AutoSPE system integrates multi-solvent delivery, cartridge compatibility, precision nitrogen drying, and direct evaporation with the SuperVap™ Concentrator. Built on the EzPrep+ control platform, it automates every step of the extraction process without the need for external software or computers.

Its intuitive touchscreen interface allows users to create, save, and run custom multi-step methods across a wide range of sample types with unmatched consistency and reliability. Automated Solid Phase Extraction – AutoSPE ensures that your lab achieves consistent and accurate results with less variability and greater efficiency.

Why Choose AutoSPE?

✅ Fully automated and programmable solid phase extraction system
✅ Integrated with SuperVap™ for GC/LC-ready final volume
✅ Supports multiple solvents and standard SPE cartridges
✅ Precision nitrogen drying and positive pressure flow control
✅ Processes 1 to 6 samples per batch
✅ Touchscreen operation — no PC required
✅ Compact, enclosed design for safety and lab space efficiency
✅ Eco-friendly operation with low solvent use and minimal waste

Whether you’re refining R&D protocols or scaling production, the AutoSPE system delivers dependable results and operational efficiency. Automated Solid Phase Extraction – AutoSPE gives your lab a complete solution for method development, production, and validation needs.

Specifications – AutoSPE

Sample Capacity: 1–6 samples per batch
Technology: Positive pressure SPE, multi-pump delivery
Drying: Integrated nitrogen drying
Evaporation: SuperVap™ Concentrator included
Interface: Touchscreen (no external computer required)
Cartridge Compatibility: Supports all standard SPE formats

AutoSPE – Reliable. Scalable. Efficient.

From pharmaceutical and biotech labs to environmental and food testing facilities, Automated Solid Phase Extraction – AutoSPE is your complete solution for high-quality, repeatable automated sample preparation.

👉 Learn more at: fms-inc.com/solid-phase-extraction

Key Features of AutoSPE:

Fully Programmable SPE Workflow

Customizable solvent delivery, flow rates, and drying cycles for flexible method development and production use.

Multi-Solvent & Multi-Cartridge Capability

Supports multiple solvent reservoirs and a wide variety of SPE cartridges and columns to accommodate complex sample matrices.

Precision-Controlled Nitrogen Drying

Delivers consistent drying with adjustable pressure and timing for optimal solvent removal without sample loss.

Touchscreen Interface with EzPrep+ Control

User-friendly, icon-driven interface enables easy programming, method storage, and real-time monitoring without external software.

Integrated SuperVap™ Concentrator

Automatically concentrates the final extract and transfers it directly into GC vials—streamlining workflows and reducing manual handling.

Parallel Sample Processing

Processes 1 to 6 samples simultaneously, increasing throughput and consistency for high-demand environments.

Compact, Closed System

Minimizes solvent exposure and enhances operator safety while reducing benchtop footprint and maintenance.


Applications of AutoSPE

Pharmaceutical R&D

Extract and purify active ingredients, impurities, and excipients from drug formulations.

Biotechnology

Prepare complex biological samples such as proteins, peptides, and cell culture media for downstream analysis.

Diagnostic Development

Purify biomarkers, metabolites, and therapeutic compounds from blood, serum, and other clinical samples.

Quality Control & Production

Standardize sample prep workflows for batch testing of raw materials and finished products.

Method Development & Validation

Build and refine custom SPE protocols using different cartridge chemistries and elution conditions.

Advantages for Your Lab

  • Speed and Efficiency: Complete sample preparation faster than ever while maintaining quality.

  • Regulatory Compliance: Meet strict industry standards with accurate and consistent results.

  • Resource Efficiency: Save on solvents and reduce labor costs with a fully automated process.

Automated Solid Phase Extraction for Pharmaceuticals, Biotech & Diagnostics

AutoSPE/Clinical6 – A fully automated solid phase extraction system designed for method development, R&D, and production in pharmaceutical, biotech, and diagnostic laboratories.


Automated Solid Phase Extraction for Research and Production

The AutoSPE/Clinical6 is an advanced, fully programmable automated solid phase extraction platform that supports pharmaceutical, biotech, and diagnostic applications. Equipped with multi-solvent delivery, multi-cartridge compatibility, precision nitrogen drying, and seamless integration with the SuperVap™ Concentrator, it delivers efficiency, consistency, and ease of use.

Built on the reliable EzPrep+ control platform, this automated solid phase extraction system simplifies complex SPE workflows without requiring external software or computers. Its intuitive touchscreen interface allows rapid method development and consistent execution across a range of sample matrices.


Why Choose AutoSPE/Clinical6 for Automated Solid Phase Extraction?

✅ Fully programmable automated solid phase extraction with multi-step method support
✅ Integrated SuperVap™ Concentrator for direct extract reduction into GC-ready vials
✅ Multi-solvent, multi-cartridge compatibility for flexible method optimization
✅ Controlled nitrogen drying ensures consistent results and efficient evaporation
✅ Parallel processing of 1 to 6 samples in 30–45 minutes per batch
✅ Touchscreen interface — no external computer or software required
✅ Compatible with standard SPE cartridges and chemistries
✅ Compact, closed design enhances safety and uptime
✅ Low solvent use supports green lab initiatives

Whether you’re optimizing extraction protocols or scaling validated methods, AutoSPE/Clinical6 delivers the precision and flexibility required for modern automated solid phase extraction in R&D and production environments.


Specifications – AutoSPE/Clinical6

Sample Capacity: 1–6 samples per run
Technology: Positive pressure, multi-pump control
Drying: Precision nitrogen drying
Evaporation: Integrated SuperVap™ Concentrator
User Interface: Touchscreen display
Cartridge Compatibility: Supports all standard SPE cartridges


Automated Solid Phase Extraction, Simplified

The AutoSPE/Clinical6 eliminates manual steps by integrating extraction, drying, and concentration into a compact, reliable platform. It provides unmatched flexibility for any lab conducting automated solid phase extraction in pharmaceutical, biotech, or diagnostic settings.

Key Features for Pharmaceutical, Biotech & Diagnostic Applications

Fully Programmable SPE Workflow
Customizable solvent delivery, flow rates, and drying cycles for flexible method development and production use.

Multi-Solvent & Multi-Cartridge Capability
Supports multiple solvent reservoirs and a wide variety of SPE cartridges and columns to accommodate complex sample matrices.

Precision-Controlled Nitrogen Drying
Delivers consistent drying with adjustable pressure and timing for optimal solvent removal without sample loss.

Touchscreen Interface with EzPrep+ Control
User-friendly, icon-driven interface enables easy programming, method storage, and real-time monitoring without external software.

Integrated SuperVap™ Concentrator
Automatically concentrates the final extract and transfers it directly into GC vials—streamlining workflows and reducing manual handling.

Parallel Sample Processing
Processes 1 to 6 samples simultaneously, increasing throughput and consistency for high-demand environments.

Compact, Closed System
Minimizes solvent exposure and enhances operator safety while reducing benchtop footprint and maintenance.


Applications

The AutoSPE/Clinical6 system supports a broad range of laboratory applications, including:

Pharmaceutical R&D:
Extract and purify active ingredients, impurities, and excipients from drug formulations.

Biotechnology:
Prepare complex biological samples such as proteins, peptides, and cell culture media for downstream analysis.

Diagnostic Development:
Purify biomarkers, metabolites, and therapeutic compounds from blood, serum, and other clinical samples.

Quality Control & Production:
Standardize sample prep workflows for batch testing of raw materials and finished products.

Method Development & Validation:
Build and refine custom SPE protocols using different cartridge chemistries and elution conditions.

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About FMS

Fluid Management Systems (FMS) specializes in designing, manufacturing, and marketing state-of-the-art sample preparation systems that are simple, quick, and cost-effective. Our comprehensive solutions encompass extraction, cleanup, and concentration processes, delivering total sample preparation from sample to vial. With a range of high-speed, high-throughput systems, we cater to various budgets and needs, ensuring efficient and reliable sample analysis. ​fms-inc.com

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FLUID MANAGEMENT SYSTEMS, INC. 900 Technology Park Drive BILLERICA, MA 01821 T: +1 (617) 393-2396 F: +1 (617) 393-0194 BY E-MAIL: FOR ALL SALES INQUIRIES: SALES@FMS-INC.COM